Tuberculosis research in India
نویسندگان
چکیده
Tuberculosis is a highly prevalent infectious disease and globally, India is one of the 22 high-burden countries. There are diagnostics and drugs available and vaccine initiatives to control the disease. However, the need of the hour is improved Point of Care diagnostic; less toxic but cheaper drug of short duration and a new vaccine is of utmost importance. Also, other areas need to be strengthened. For these, research efforts are ongoing and Indian researchers have been involved in several diversified fields of this endeavour. This commentary deals with some of the notable research works in the recent past.
منابع مشابه
Pattern of ethionamide susceptibility and its association with isoniazid resistance among previously treated tuberculosis patients from India.
1MSc, Senior Research Fellow, Department of Bacteriology, Tuberculosis Research Centre, India 2PhD, Scientist F, Department of Bacteriology, Tuberculosis Research Centre, India 3BSc, Laboratory Technician, Department of Bacteriology, Tuberculosis Research Centre, India 4Senior Technical Officer A, Department of Bacteriology, Tuberculosis Research Centre, India 5MSc, Scientist D, Department of B...
متن کاملDevelopment of 1,2,4-triazole-5-thione derivatives as potential inhibitors of enoyl acyl carrier protein reductase (InhA) in tuberculosis.
Tuberculosis (TB) ranks second, next to AIDS making it most formidable disease if the present age. One of the crucial enzymes involved in cell wall synthesis of Mycobacterium tuberculosis, InhA (enoyl acyl carrier protein reductase) has been authenticated as an effective target for anti-mycobacterial drug development. In the current work, we have developed novel derivatives of 1,2,4-triazole-5-...
متن کاملTubercular Otitis Externa in an Elderly Male- A Case Report
Introduction: Tuberculosis is one of the most common diseases in developing countries, resulting in significant morbidity and mortality. Tuberculosis has varied clinical presentations, varying from common primary pulmonary tuberculosis to the extremely rare tubercular otitis externa, as in this case. Tubercular otitis externa has an extremely low clinical incidence. Case Report: We report the...
متن کاملFostering Directly Observed Treatment in Tuberculosis: A Program Manager’s Perspective
Global Tuberculosis (TB) report (2013) has revealed that an estimated 8.6 million people developed TB of which, India accounts for almost 26% of the cases. These estimates clearly suggest that the country’s efforts to achieve Millennium Development Goal 6 by 2015 have not delivered the desired output. In India, the TB prevention and control activities are supervised and implemented under the Re...
متن کاملDetection of Isoniazid-Resistant Clinical isolates of Mycobacterium tuberculosis from India using Ser315Thr marker by Comparison of molecular methods
In this study, Substitution at codon Ser315 of katG gene, a reliable marker for isoniazid (INH) resistance was analyzed and compared by three molecular methods such as DNA sequencing, polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) and PCR-single strand conformation polymorphism (PCR-SSCP) in 105 phenotypically resistant isolates obtained from various parts of Ind...
متن کاملNaso-Septal Tuberculosis Mimicking Dermoid in a 3-Year old Child
Introduction: Tuberculosis is a communicable disease caused by mycobacterium tuberculosis that primarily affects the lungs. Primary tuberculosis of the nose in the pediatric age group is rare. The diagnosis of this common entity in the present case was challenging. Case Report: We report the case of a 3-year old girl who presented with a painless swelling over the dorsum of the nose for 7 mon...
متن کامل